{"product_id":"crystagen","title":"Crystagen","description":"\u003ch3\u003eCrystagen (EDP) Peptide\u003c\/h3\u003e\n\u003ch3\u003e1. Basic Profile\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eCrystagen, also known as \u003c\/span\u003e\u003cstrong\u003eEDP (Glu-Asp-Pro)\u003c\/strong\u003e\u003cspan\u003e, is a synthetic tripeptide bioregulator developed by Professor Vladimir Khavinson’s research group at the St. Petersburg Institute of Bioregulation and Gerontology. It belongs to the tissue-specific short peptide bioregulator family.\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAmino Acid Sequence: L-Glutamyl-L-Aspartyl-L-Proline (Glu-Asp-Pro, EDP)\u003c\/li\u003e\n\u003cli\u003eMolecular Weight: 359.33 Da\u003c\/li\u003e\n\u003cli\u003eForm: Lyophilized white powder\u003c\/li\u003e\n\u003cli\u003eHalf-life: Short in circulation (approx. 30 minutes). Its epigenetic regulatory effects persist long after the peptide is cleared from blood.\u003c\/li\u003e\n\u003cli\u003eCore Target Tissue: Thymus gland and systemic immune cells (lymphocytes, macrophages, NK cells)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eCrystagen is an active fragment isolated from Thymalin (thymus polypeptide extract). It regulates immune cell gene expression at the nuclear level instead of only binding to cell surface receptors.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e2. Mechanism of Action\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003ePenetrates immune cell membranes and enters cell nuclei to interact with DNA and histone proteins, epigenetically activating silenced genes linked to immune function.\u003c\/li\u003e\n\u003cli\u003eSupports thymic epithelial cell viability, reduces thymocyte apoptosis, slows age-related thymus involution.\u003c\/li\u003e\n\u003cli\u003eStimulates T-lymphocyte differentiation, balances CD4+\/CD8+ ratio, improves innate and adaptive immune activity.\u003c\/li\u003e\n\u003cli\u003eModulates cytokine secretion, relieves chronic low-grade inflammation; elevates HSP70 heat shock protein expression to enhance cellular stress resistance.\u003c\/li\u003e\n\u003cli\u003ePromotes normal lymphocyte proliferation while suppressing abnormal proliferation of tumor cell lines observed in preclinical models.\u003c\/li\u003e\n\u003cli\u003eAssists immune reconstruction after infection, radiation, surgery or prolonged stress.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch3\u003e3. Main Observed Research Effects\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eRestore immune function in aging and immunosuppression models\u003c\/li\u003e\n\u003cli\u003eReduce frequency of acute respiratory infections\u003c\/li\u003e\n\u003cli\u003eAccelerate physical recovery after illness and surgical trauma\u003c\/li\u003e\n\u003cli\u003eBalance inflammatory response and enhance antiviral defense\u003c\/li\u003e\n\u003cli\u003eDelay immunosenescence (age-related immune decline)\u003c\/li\u003e\n\u003cli\u003eImprove stress resilience by stabilizing immune-endocrine crosstalk\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e4. Reconstitution Instructions (Lyophilized Vial)\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eCommon specifications: \u003c\/span\u003e\u003cstrong\u003e10mg \/ 20mg per vial\u003c\/strong\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eAllow the peptide vial to reach room temperature; sterilize rubber stopper with alcohol wipe.\u003c\/li\u003e\n\u003cli\u003eSlowly inject Bacteriostatic Water (BAC water) along the inner wall of the vial, avoid direct impact onto lyophilized powder.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cdiv\u003eRecommended mixing scheme: 10mg powder + 2mL BAC water → Concentration = 5 mg\/mL\u003c\/div\u003e\n\u003col start=\"3\"\u003e\n\u003cli\u003eGently rotate the vial to dissolve powder.\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003eDO NOT shake violently to prevent peptide degradation and foaming.\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eFinal solution is clear and colorless.\u003c\/li\u003e\n\u003cli\u003eStorage Requirements\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cul\u003e\n\u003cli\u003eUnreconstituted lyophilized powder: Store sealed at -20°C, protected from light. Shelf life up to 24 months.\u003c\/li\u003e\n\u003cli\u003eReconstituted peptide solution: Refrigerate 2°C ~ 8°C, stable within 28 days. Avoid repeated freeze-thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003e5. Research Administration Protocols\u003c\/h3\u003e\n\u003ch3\u003ePrimary Route: Subcutaneous Injection\u003c\/h3\u003e\n\u003ch3\u003eReference Experimental Dosage\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAdaptation phase:\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e500 mcg (0.5 mg) daily\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eStandard maintenance dosage:\u003cspan\u003e \u003c\/span\u003e\u003cstrong\u003e1000 mcg – 2000 mcg (1–2 mg) daily\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003eInjection site: Lower abdomen subcutaneous tissue; rotate injection positions regularly\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eCycle Schedule\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eStandard cycle: \u003c\/span\u003e\u003cstrong\u003e10–20 consecutive days on cycle\u003c\/strong\u003e\u003cspan\u003e After finishing one cycle, pause for 3–6 months before starting a new round of administration.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eAlternative Research Delivery Route\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eIntranasal administration: Reference working concentration 0.25–1 mg\/mL, once daily for mucosal immune research.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003e6. Precautions\u003c\/h3\u003e\n\u003col\u003e\n\u003cli\u003ePure laboratory research reagent. Not approved for human medical use.\u003c\/li\u003e\n\u003cli\u003eStrict sterile operation required during reconstitution to avoid bacterial contamination.\u003c\/li\u003e\n\u003cli\u003eDiscard solution immediately if turbidity, precipitation or persistent local irritation occurs.\u003c\/li\u003e\n\u003cli\u003eMost supporting data comes from preclinical cell and animal experiments; large-scale independent human clinical research remains limited.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003chr\u003e\n\u003ch3\u003eShort Version (For Product Page \/ WhatsApp \/ Customer Direct Message)\u003c\/h3\u003e\n\u003ch3\u003eCrystagen (EDP) Peptide\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eCrystagen (EDP) is a Khavinson-series tripeptide bioregulator targeting the thymus and systemic immune system. It enters immune cell nuclei to regulate gene expression, widely studied for immune restoration, anti-infection support, anti-immunosenescence and post-injury recovery.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eReconstitution\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003eDissolve lyophilized powder with bacteriostatic water. Rotate gently to dissolve without violent shaking.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eReference Subcutaneous Research Dosage\u003c\/h3\u003e\n\u003cp\u003e\u003cspan\u003e0.5mg–2mg once daily. Standard cycle: 10–20 days on, rest 3–6 months before reuse.\u003c\/span\u003e\u003c\/p\u003e","brand":"我的商店","offers":[{"title":"20mg*10vials","offer_id":53703826800940,"sku":null,"price":55.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0979\/1406\/1100\/files\/a49886046c963c990ab58cb192013a99bc3c5b664a30fa663ae704be12fac003.png?v=1786605007","url":"https:\/\/0rw2.com\/products\/crystagen","provider":"0rw2.com","version":"1.0","type":"link"}